ISOLATION AND IDENTIFICATION OF FATTY ACID AND THE DERIVATIVES FROM BITTER MELON (MOMORDICA CHARANTIA) SEED
Indonesia is one of many tropical countries endowed with a bunch variety of flora. Bitter melon <br /> <br /> (Momordica charantia) is one plant out of tons which is thriving in Indonesia. It is commonly <br /> <br /> utilized as food and traditional medicine. One group of co...
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Format: | Final Project |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/28236 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |
Summary: | Indonesia is one of many tropical countries endowed with a bunch variety of flora. Bitter melon <br />
<br />
(Momordica charantia) is one plant out of tons which is thriving in Indonesia. It is commonly <br />
<br />
utilized as food and traditional medicine. One group of compound that is biologically active in <br />
<br />
bitter melon is its unsaturated fatty acid. Unsaturated fatty acid in bitter melon was reported to be <br />
<br />
able to suppress cancer growth and stimulate lipid metabolism in human body. To get a full <br />
<br />
benefit from bitter melon, phytochemical research is needed. In this project, fatty acid and its <br />
<br />
derivatives were isolated from 0.520 kg of dry bitter melon seeds. The seeds were macerated <br />
<br />
with methanol (3x24 hours). Fractionation of methanol extract was done by the means of liquid <br />
<br />
vacuum chromatography, radial chromatography, and gravity column chromatography. Each <br />
<br />
isolated compound was characterized with 1H-NMR and 13C-NMR. In this project, there are <br />
<br />
three compounds that were managed to be isolated and characterized. They are α-eleostearic <br />
<br />
acid, glyceryl-1,3-di-α-eleostearate-2-behenate and glyceryl-1,2-α-palmtitate |
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