#TITLE_ALTERNATIVE#
Ischemic stroke is the most prevalent type of stroke. The risk of stroke recurrence <br /> <br /> is increased in patients who have previous stroke episode. Antiplatelet therapy <br /> <br /> could prevent stroke recurrency. This study aimed to assess efficacy antiplatelet in...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/30092 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | Ischemic stroke is the most prevalent type of stroke. The risk of stroke recurrence <br />
<br />
is increased in patients who have previous stroke episode. Antiplatelet therapy <br />
<br />
could prevent stroke recurrency. This study aimed to assess efficacy antiplatelet in <br />
<br />
preventing recurrence stroke in ischemic stroke patients and to identify adverse <br />
<br />
drug reactions (ADRs) occurred during treatment. This study was a prospective <br />
<br />
cohort study with internal comparator. Subjects were recruited with nonprobability method using consecutive sampling, resulting in a total of 45 subjects. <br />
<br />
After three months of antiplatelet use, stroke recurrence occurred in 1 subject <br />
<br />
(5%) under acetosal, and 8 subjects (40%) in antiplatelet discontinuation before 3 <br />
<br />
months. Significant difference (p<0.05) was observed between acetosal users and <br />
<br />
drug discontinuing subjects during the three-month study. During acetosal use the <br />
<br />
following ADRs occurred, heartburn (13.95%), nausea (6.98%), ecchimosis <br />
<br />
(4.65%) and reduced skin turgor (2.36%). The results suggest that acetosal is <br />
<br />
effective in preventing stroke recurrence only 26,83% the accompanying ADRs <br />
<br />
that include heartburn, nausea, dehidration and ecchimosis. <br />
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