#TITLE_ALTERNATIVE#

• Main Author: RETNO ARIANI NIM: 20716028, RADEN
• Format: Theses
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/30092
• Institution: Institut Teknologi Bandung

Ischemic stroke is the most prevalent type of stroke. The risk of stroke recurrence <br /> <br /> is increased in patients who have previous stroke episode. Antiplatelet therapy <br /> <br /> could prevent stroke recurrency. This study aimed to assess efficacy antiplatelet in <br /> <br /> preventing recurrence stroke in ischemic stroke patients and to identify adverse <br /> <br /> drug reactions (ADRs) occurred during treatment. This study was a prospective <br /> <br /> cohort study with internal comparator. Subjects were recruited with nonprobability method using consecutive sampling, resulting in a total of 45 subjects. <br /> <br /> After three months of antiplatelet use, stroke recurrence occurred in 1 subject <br /> <br /> (5%) under acetosal, and 8 subjects (40%) in antiplatelet discontinuation before 3 <br /> <br /> months. Significant difference (p<0.05) was observed between acetosal users and <br /> <br /> drug discontinuing subjects during the three-month study. During acetosal use the <br /> <br /> following ADRs occurred, heartburn (13.95%), nausea (6.98%), ecchimosis <br /> <br /> (4.65%) and reduced skin turgor (2.36%). The results suggest that acetosal is <br /> <br /> effective in preventing stroke recurrence only 26,83% the accompanying ADRs <br /> <br /> that include heartburn, nausea, dehidration and ecchimosis. <br />