#TITLE_ALTERNATIVE#

• Main Author: Khairani NIM : 20214030, Rizki
• Format: Theses
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/30588
• Institution: Institut Teknologi Bandung

<p align="justify">This reaserch investigate the DNA-solvent interaction in the Peyrard-Bishop modelwhich focus on twisting and stretching DNA base pair motions. The dynamics ofthis system will be drawn from the solitary wave solution by using multiple scale <br /> <br /> expansion to the case of the vectorial lattice. The solvent effect is studied analyticallyand numerically, the breather-soliton is the solution for the stretching motionand the kink-soliton is the solution for the twisting motion. We found that the strength <br /> <br /> and the effective length the solvent interaction affect length and amplitude ofthe envelope. Solvent change the stability of the breath state (bubble formation) in <br /> <br /> the stretching motion. A positive value of solvent barier factor give the reshuffleof the base-pairs opening in stable condition moves to a positive value, means thehydrogen bond stretch. For twisting motion, we obtain the well of the kink-solitonafter adding the solvent, deeper than before, indicated the strand arc length which makes the DNA more winded, while a negative value gives the opposite effects.<p align="justify">