#TITLE_ALTERNATIVE#

• Main Author: GHASSANI NIM : 11614040, SHABRINA
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/30902
• Institution: Institut Teknologi Bandung

The wise use of antibiotics must be adjusted to the sensitivity pattern of bacterial to antibiotics in the <br /> <br /> treatment room. These efforts can prevent bacterial resistance to antibiotics. Intensive care unit (ICU) <br /> <br /> was chosen to create a sensitivity pattern, because it treated patients with critical conditions so that they <br /> <br /> needed rapid therapy. In addition, class III inpatient rooms were chosen because the room uses most <br /> <br /> antibiotics. This study aims to determine sensitivity patterns and examine the shift in bacterial sensitivity <br /> <br /> to antibiotics in both rooms. This study is an observational study using data from laboratory installations <br /> <br /> with retrospective design in ICU patients and class III inpatient rooms in four periods (each period is 6 <br /> <br /> months) from January 2016 - December 2017. The bacteria were categorized as resistant if the antibiotic <br /> <br /> sensitivity percentage is &#8804;40%. To determine the significance of the shift in antibiotic sensitivity to <br /> <br /> bacteria, the Chi-square analysis method (significance level 0.05) was used. The total number of samples <br /> <br /> showing positive culture results was 530, which came from various specimens namely sputum, pleural <br /> <br /> fluid, bronchial rinses, blood, pus, feces, wound smears, and vaginal swabs. The most common bacteria <br /> <br /> found in both rooms during the study period was Staphylococcus spp. The sensitivity pattern of bacterial <br /> <br /> to antibiotics was made for the four test periods in each room, it is known that there are bacteria that are <br /> <br /> resistant to the first choice of antibiotics, but there are still antibiotics that are still sensitive, so that <br /> <br /> antibiotics can be recommended to doctors as a treatment option. There was a shift in bacterial sensitivity <br /> <br /> to alternative antibiotics which was statistically significant for Staphylococcus spp and Enterobacter <br /> <br /> cloacae bacteria in the ICU and in class III inpatient rooms. <br />