TOXICITY EVALUATION OF SLUDGE FROM WWTP OF THE CIGARETTE INDUSTRY TO RATS (Rattus norvegicus) AND MICE (Mus musculus)
One of the problems of the cigarette industry is a solid waste generated from the wastewater treatment plant. Solid waste is also called sludge. A sludge is resulted from a coagulation and flocculation process. Cigarette industrial wastewater treatment of PT. X produced in relatively big amount o...
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| Format: | Theses |
| Language: | Indonesia |
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| Online Access: | https://digilib.itb.ac.id/gdl/view/32082 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | One of the problems of the cigarette industry is a solid waste generated from the
wastewater treatment plant. Solid waste is also called sludge. A sludge is resulted
from a coagulation and flocculation process. Cigarette industrial wastewater
treatment of PT. X produced in relatively big amount of sludge (approximately
15,000 kg/month), it was not tested yet on security level. Some physics and
chemistry tests are not sufficient enough to assess a pollution impact for living
organisms; therefore, biomonitoring such as toxicity test is required. Toxicity test
were applying to a mice and rats as an animal test that consists of a Test
Characteristic Leaching Procedure (TCLP), an acute test and a subchronic test.
The results of chemical test were compared descriptively with a quality standard
of TCLP (issued by the USEPA and PP. No. 85/1999), and the acute toxicity
refers LD50 value (issued by the PP. No. 85/1999) while the subchronic toxicity
testing was analyzed statistically using a one-way ANOVA method (?=0.05). This
study showed that the heavy metals concentration on the sludge of PT. X was very
low concentrations regarding to the maximum concentration standard (PP No.
18/1999 jo the PP No. 85/1999). The acute toxicity test found that the dose
variation of sludge did not cause a death for rats and mice. However the sludge
infusion with a dose of 500 mg/kgbw caused a decreasing of a mice’s body weight
and a dose of 5000 mg/kgbw caused a decreasing of a rats’s body weight. In
addition, the subchronic test indicated that a sludge exposure with a dose of 50
mg/kgbw to the female mices were able to increase a degeneration and a necrosis
of kidney and liver cell in which significantly different from controls. |
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