Purification, Crystallization, and Modelling of Mutant Catalase-Peroxidase from Isoniazid Resistant Mycobacterium tuberculosis
Catalase-peroxidase (KatG) from Mycobacterium tuberculosis (Mtb) is a bifunctional enzyme that has been shown to activate isoniazid (INH), a pro-drug that is important for antituberculosis treatment. KatG is encoded by a katG gene which could undergo mutations to cause a decrease in the KatG activit...
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| Format: | Final Project |
| Language: | Indonesia |
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| Online Access: | https://digilib.itb.ac.id/gdl/view/32231 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |