Theoretical insights on the binding of isoniazid to the active site residues of mycobacterium tuberculosis catalase-peroxidase

Isoniazid (INH) is known to cause the exclusive lethal action to Mycobacterium tuberculosis (M. tb.) cells because of the pathogen's own catalase-peroxidase (katG) enzyme that converts INH to a very reactive radical. Thus, in order to gain insights on the interaction of INH with the individual...

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Bibliographic Details
Main Authors: Reyes, Yves Ira A., Janairo, Gerardo C., Franco, Francisco C., Jr.
Format: text
Published: Animo Repository 2019
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/2892
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Institution: De La Salle University