ANTIBACTERIAL ACTIVITY OF EXTRACT AND SELECTED FRACTION FROM MERANG MUSHROOM, GARLIC, TEMU PUTIH AND TEMU MANGGA AGAINST SOME PATHOGENIC BACTERI

• Main Author: Syarifah, Nala
• Format: Theses
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/44071
• Institution: Institut Teknologi Bandung

Infectious diseases is one of the health problems that cause the most significant morbidity and mortality, especially in Indonesia as developing country. Commonly treatment of infection did by antibiotic therapy, but there were several cases of resistances, so encourage us to develop alternative treatments using natural ingredients. Merang mushroom, garlic, temu putih and temu mangga thought have antibacterials activity. This research aimed for knowing antibacterial activity from those extract and selected fraction with diffusion papper disk methode, and broth microdilution methode. Inhibitory of 96% ethanol extract of a temu mangga showed the best activity against S. aureus and B. cereus with consecutive MIC 1024 ppm and 256 ppm. The best MIC was shown by the n-hexane fraction temu mangga at 64 ppm against B. cereus. According equality data, that 1 mg n-hexane fraction of temu mangga equivalent to 0,073 mg tetracycline as antibacterial comparison.