UJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC.

UJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC.

<b>Abstract: <p align=\"justify\"> <br /> <br /> The antiallergic activity of sambiloto (Andrographis paniculta Nees., family Acanthaceae)and sembung (Bluma balsmifera (L) DC., family Compocitae) leaves on the isolated guinea-pig ileum, mast cell degranulation an...

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Main Author: Aldi, Yufri
Format: Theses
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/4501
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Institution: Institut Teknologi Bandung
Language: Indonesia
id id-itb.:4501
spelling id-itb.:45012006-03-16T10:30:40ZUJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC. Aldi, Yufri Indonesia Theses INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/4501 <b>Abstract: <p align=\"justify\"> <br /> <br /> The antiallergic activity of sambiloto (Andrographis paniculta Nees., family Acanthaceae)and sembung (Bluma balsmifera (L) DC., family Compocitae) leaves on the isolated guinea-pig ileum, mast cell degranulation and systemic anaphylaxis methods has been studied. From the ethanol extracts, three fractions were obtained i.e. petroleum eter, chloroform and acid fraction. The acid fractions of each plant significantly (P<0,01) inhibited contractile respons caused by histamine at concentrations of 7,4-73,9 ug/ml; significantly (P,0,01) prevented mast cell degranulation effect of compound 48/80 at concentration of 0,01-0,1% (w/v) and protected active cutaneous anaphylaxis induced by ovalbumine in mice at dose of 100-800 mg/kg body weight. Both the petroleum ether and the chloroform fractions did not show antiallergic activity. It was shown that sambiloto and sembung leaves showed antiallergic activity in vitro as well as in vivo.<p align=\"justify\"> text
institution Institut Teknologi Bandung
building Institut Teknologi Bandung Library
continent Asia
country Indonesia
Indonesia
content_provider Institut Teknologi Bandung
collection Digital ITB
language Indonesia
description <b>Abstract: <p align=\"justify\"> <br /> <br /> The antiallergic activity of sambiloto (Andrographis paniculta Nees., family Acanthaceae)and sembung (Bluma balsmifera (L) DC., family Compocitae) leaves on the isolated guinea-pig ileum, mast cell degranulation and systemic anaphylaxis methods has been studied. From the ethanol extracts, three fractions were obtained i.e. petroleum eter, chloroform and acid fraction. The acid fractions of each plant significantly (P<0,01) inhibited contractile respons caused by histamine at concentrations of 7,4-73,9 ug/ml; significantly (P,0,01) prevented mast cell degranulation effect of compound 48/80 at concentration of 0,01-0,1% (w/v) and protected active cutaneous anaphylaxis induced by ovalbumine in mice at dose of 100-800 mg/kg body weight. Both the petroleum ether and the chloroform fractions did not show antiallergic activity. It was shown that sambiloto and sembung leaves showed antiallergic activity in vitro as well as in vivo.<p align=\"justify\">
format Theses
author Aldi, Yufri
spellingShingle Aldi, Yufri
UJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC.
author_facet Aldi, Yufri
author_sort Aldi, Yufri
title UJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC.
title_short UJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC.
title_full UJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC.
title_fullStr UJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC.
title_full_unstemmed UJI EFEK ANTIALERGI DARI TUMBUHAN ANDROGRAPHIS PANICULATA NEES. DAN BLUMEA BALSAMIFERA (L) DC.
title_sort uji efek antialergi dari tumbuhan andrographis paniculata nees. dan blumea balsamifera (l) dc.
url https://digilib.itb.ac.id/gdl/view/4501
_version_ 1820663413910536192

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