DEVELOPMENT OF BIOSIMILAR RECOMBINANT HUMAN INTERFERON-?2B THROUGH PERIPLASM EXPRESSION
Human recombinant interferon alfa2b (rhIFN?2b) as a biosimilar product must have an identic amino acid sequence to the native form. Unauthenticity of N-terminal amino acid can be overcomed by peripasmic expression. Construction of recombinant plasmid genes to transformation into E. coli TOP10 had...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/45230 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |