POLA RESISTENSI BAKTERI TERHADAP ANTIBIOTIK DI UNIT PERAWATAN INTENSIF SALAH SATU RUMAH SAKIT SWASTA DI BANDUNG

• Main Author: Laila Miza, Hidayatul
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/45517
• Institution: Institut Teknologi Bandung

Intensive Care Unit (ICU) is an unit in the hospital where seriously ill patients are cared with specialised monitoring equipment. One of the drugs used in the ICU are antibiotics. The appropiate antibiotic should be given in a spesific patients infected by bacteria in order to reduce the adverse effects of inappropiate antibiotics. Therefore, it is necessary to have the the actual resistance pattern. This study aims to determine the antibiotic resistance pattern and to assess the antibiotic sensitivity trends in the ICU, where was divided into three units, ICU (general), Neonatus ICU / Pediatric ICU (NICU/PICU), and Stroke Unit (SU). This study was a retrospective observational study. The antibiotic resistance pattern study was carried out in the period of October to December 2014 and antibiotic sensitivity trends study was carried out in the period of January to December 2014. Resistance of bacteria ensue if sensitive percentation about <50%. Chi-square analysis (level of significancy (p)=0,05) method was used to assess the significancy of antibiotic sensitivity trends. There were 112 specimens used in resistance pattern study which consist of smear, bullion, fluids, blood, pus, sputum, swabs, urine, fluid umbilicus, cerebrospinal fluid (CSF), secretions, tip, and vaginal secretions. Bacteria that have the highest prevalence of resistance is Acinetobacter baumannii (ICU) 100%, Klebsiella pneumoniae (ESBL) (NICU / PICU) 80%, and Citrobacter freundii (SU) 100%. There were 526 specimens used in the antibiotic sensitivity trends. The sensitive to resistance bacteria trends showed by Acinetobacter baumannii and Pseudomonas aeruginosa (ICU), Acinetobacter baumannii and Klebsiella pneumoniae (ESBL) (SU). The resistance to sensitive bacteria trends showed by is Pseudomonas aeruginosa (ICU), Klebsiella pneumoniae ss. Pneumonia (NICU / PICU), Acinetobacter baumannii (SU).