TELAAH PUSTAKA PEMANFAATAN TUMBUHAN HERBAL INDONESIA SEBAGAI ANTIOBESITAS

• Main Author: Putri Sobandi, Aulia
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/50521
• Institution: Institut Teknologi Bandung

Obesity and overweight occurs when there is an imbalance between energy intake and energy expenditure over time resulting in increased energy storage. Nowadays there are some medications have been used to treat obesity, however there is a limit to their long-term application because of severe side effects. Many studies have confirmed that herbal medicine is effective in the treatment for obesity. This literature review performed to compile data of Indonesia's herbal plants that have been reported in the past decade used search engine Google Scholar and Pubmed with antiobesity activities proved by pre-clinical or clinical studies and have the potential to be alternative drugs from orlistat. Journal selected based on inclusion criteria such as international journal or national, with English or Indonesian language, published in the last ten years, full text or free full text. Exclusion criteria such plants didn’t cultivated in Indonesia, an isolate, or effect from combination of several herbs. From the search result, 30 herbal medicines from 20 Famili that are useful for weight loss or antiobesity were selected such as Allium cepa L., Allium fistulosum L., Allium sativum L., Aloe vera (L.) Burm. f., Annona muricata L., Anredera cordifolia (Ten.) Steenis., Camellia sinensis (L.) Kuntze., Chrysanthemum morifolium Ramat., Coffea Arabica L., Cosmos caudatus Kunth., Crocus sativus L., Curcuma longa L., Eleutherine bulbosa (Mill.) Urb., Ficus carica L., Foeniculum vulgare Mill., Garcinia mangostana L., Glycine max (L.) Merr., Glycyrrhiza glabra L., Hibiscus sabdariffa L., Momordica charantia L., Morinda citrifolia L., Morus alba L., Myristica fragrans Houtt., Nelumbo nucifera Gaertn., Oryza sativa L., Phaseolus vulgaris L., Sauropus androgynus (L.) Merr., Syzygium aromaticum (L.) Merr & Perry., Tamarindus indica L., Zingiber officinale Roscoe. From 30 herbal medicine, only 13 have passed clinical trials. Some of them can be recommended for further studies by looking the parameters of the dose, duration, and the design trial. The results indicate that Zingiber officinale Roscoe and Crocus sativus L extract can induce weight loss in a short time period and in low dose without side effect.