EVALUASI PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN HEMODIALISIS DI SALAH SATU RUMAH SAKIT SWASTA DI BANDUNG

• Main Author: Aprilia, Stephanie
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/62166
• Institution: Institut Teknologi Bandung

Kidney has an important role in regulating body homeostasis. Kidney disease is one of „silent epidemic?disease that affects many people around the world. There is a good relationship between hypertension and kidney disease. Hypertension can be a cause of kidney disease, and in another hand, also can be an impact of kidney disease. High blood pressure need to be well controlled so that it will not aggravate renal damage especially hemodialysis patients who had suffered end-stage renal disease. This study was aimed to evaluate the profile of antihypertensive drugs in hemodialysis patients in one of the private hospitals in Bandung. This study was a retrospective descriptive observational study by collecting data from daily data of hemodialysis patients during the period from October to December 2012. Based on descriptive data, there were 68 people who used antihypertensive drugs and also got hemodialysis as a renal replacement therapy. Most of them were diagnosed end stage renal disease with hypertension as an initiation factor. One of antihypertensive drugs which most widely used was Calcium Channel Blocker (CCB) either in single use (17.65%) or in combination with other antihypertensive drugs (61.75%). Overall, the appropriateness of drug selection was 76.47% and the inappropriateness of drug selection was 23.53% due to inappropriate use of HCT. The accuracy of drug dosing in patients was 86.47% and the inaccuracy was 13.53%. Other medication that most widely used were anti-anemia supplements (42.65%), erythropoietin hormone (38.24%), and calcium supplements (32.35%). There were 2 potential cases of drug duplication known as the use of two drugs from CCB class and two drugs from diuretic class. There were 3 potential cases of the inappropriate combination of ACE Inhibitor and ARB simultaneously. Based on this research, the use of antihypertensive drugs in hemodialysis care unit in one of the private hospital in Bandung is appropriate, both in the drug choice and drug dosage.