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ABSTRACT: <br /> <br /> <br /> <br /> The effect of ethanol extract of sambiloto (Andrographis paniculata Nees.) herbs and red fruit (Pandanus conoideus Lam.) oil on non-specific and specific immune response had been studied in female Swiss Webster mice. The sambiloto extr...
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Format: | Final Project |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/6548 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |
Summary: | ABSTRACT: <br />
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The effect of ethanol extract of sambiloto (Andrographis paniculata Nees.) herbs and red fruit (Pandanus conoideus Lam.) oil on non-specific and specific immune response had been studied in female Swiss Webster mice. The sambiloto extract was administered orally at doses of 135 and 68 mg/kg body weight and the red fruit oil at doses of 0,65 dan 0,32 mL/kg body weight daily, for 7 concecutive days. On the test against non-specific immune response by clearance carbon method, the extract of sambiloto at a dose of 135 mg/kg body weight showed a strong immunostimulant effect with fagocytic index 1,857. The test on specific immune response showed that the extract of sambiloto at a dose of 135 mg/kg body weight and the two doses of red fruit oil increased the antibody titer as a humoral immune response. The test on cellular immune response showed that the extract of sambiloto at a dose of 135 mg/kg body weight increased the cellular immune response while the red fruit oil at a dose of 0,65 mL/kg body weight decreased the cellular immune response significantly (p less than 0,05). |
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