#TITLE_ALTERNATIVE#

• Main Author: SAKINAH (NIM: 10702018), NONGKI
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/6548
• Institution: Institut Teknologi Bandung

ABSTRACT: <br /> <br /> <br /> <br /> The effect of ethanol extract of sambiloto (Andrographis paniculata Nees.) herbs and red fruit (Pandanus conoideus Lam.) oil on non-specific and specific immune response had been studied in female Swiss Webster mice. The sambiloto extract was administered orally at doses of 135 and 68 mg/kg body weight and the red fruit oil at doses of 0,65 dan 0,32 mL/kg body weight daily, for 7 concecutive days. On the test against non-specific immune response by clearance carbon method, the extract of sambiloto at a dose of 135 mg/kg body weight showed a strong immunostimulant effect with fagocytic index 1,857. The test on specific immune response showed that the extract of sambiloto at a dose of 135 mg/kg body weight and the two doses of red fruit oil increased the antibody titer as a humoral immune response. The test on cellular immune response showed that the extract of sambiloto at a dose of 135 mg/kg body weight increased the cellular immune response while the red fruit oil at a dose of 0,65 mL/kg body weight decreased the cellular immune response significantly (p less than 0,05).