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Abstract: <br /> <br /> <br /> <br /> Glybenclamide results in related substances under its degradation. Therefore for quality evaluation of glybenclamide bulk it needs such impurity references standard. To make a related substance, glybenclamide was refluxed in methanol f...

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Main Author: Noviarlis (NIM:107 03 080), Wantari
Format: Final Project
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/6887
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Institution: Institut Teknologi Bandung
Language: Indonesia
id id-itb.:6887
spelling id-itb.:68872012-06-18T15:01:27Z#TITLE_ALTERNATIVE# Noviarlis (NIM:107 03 080), Wantari Indonesia Final Project INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/6887 Abstract: <br /> <br /> <br /> <br /> Glybenclamide results in related substances under its degradation. Therefore for quality evaluation of glybenclamide bulk it needs such impurity references standard. To make a related substance, glybenclamide was refluxed in methanol for 24 hours. The result of reflux was isolated and purificated by coloumn chromatography. The isolate was characterizated by thin-layer chromatography, ultraviolet light and infrared <br /> <br /> <br /> <br /> spectrophotometry. The isolate showed a different TLC profile and infrared spectrum to that of glybenclamide. The isolate was predicted to be a methyl N-4-[2-(5-chloro-2- methoxybenzamido)ethyl] benzenesulphonylcarbamat. text
institution Institut Teknologi Bandung
building Institut Teknologi Bandung Library
continent Asia
country Indonesia
Indonesia
content_provider Institut Teknologi Bandung
collection Digital ITB
language Indonesia
description Abstract: <br /> <br /> <br /> <br /> Glybenclamide results in related substances under its degradation. Therefore for quality evaluation of glybenclamide bulk it needs such impurity references standard. To make a related substance, glybenclamide was refluxed in methanol for 24 hours. The result of reflux was isolated and purificated by coloumn chromatography. The isolate was characterizated by thin-layer chromatography, ultraviolet light and infrared <br /> <br /> <br /> <br /> spectrophotometry. The isolate showed a different TLC profile and infrared spectrum to that of glybenclamide. The isolate was predicted to be a methyl N-4-[2-(5-chloro-2- methoxybenzamido)ethyl] benzenesulphonylcarbamat.
format Final Project
author Noviarlis (NIM:107 03 080), Wantari
spellingShingle Noviarlis (NIM:107 03 080), Wantari
#TITLE_ALTERNATIVE#
author_facet Noviarlis (NIM:107 03 080), Wantari
author_sort Noviarlis (NIM:107 03 080), Wantari
title #TITLE_ALTERNATIVE#
title_short #TITLE_ALTERNATIVE#
title_full #TITLE_ALTERNATIVE#
title_fullStr #TITLE_ALTERNATIVE#
title_full_unstemmed #TITLE_ALTERNATIVE#
title_sort #title_alternative#
url https://digilib.itb.ac.id/gdl/view/6887
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