THE DEVELOPMENT OF AN INTRAVASCULAR THERAPY SIMULATION DEVICE WITH CONDITION OF REALISTIC BLOOD VESSEL

• Main Author: Ihsan Maulana, Muhammad
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/73145
• Institution: Institut Teknologi Bandung

<p align="justify"> Stroke leads to an 85% of death rate from cardiovascular disease in this world. A stroke is when brain cells will not work correctly or even stop working because brain cells do not get enough oxygen from the bloodstream. Most stroke cases are caused by plaque accumulation inside the blood vessel walls, commonly known as stenosis. One of the methods for treating stenosis is using balloon angioplasty (BA) to revascularize the blockage area of plaque layers and place the stent in the revascularized area as a scaffolding to maintain the vessel position. To the best of our knowledge, research about the virtual design of therapy instruments and virtual therapy simulation is not widely established yet. In order to reinforce the local industry, in this research, we develop an in silico simulation program to represent the actual phenomenon physically during the stenosis treatment using BA and stent. The BA deployment algorithm is virtually implemented using a spring-damper model analogy with the lineal and semitorsional spring approach. This approach allows obtaining physical information such as pressure along the blood vessel model. Thus, it can be evaluated regarding the standard clinical reference about blood vessel conditions. Consequently, the fluid profile flowing inside the blood vessel will be evaluated by Computational Fluid Dynamics (CFD) to see several physical parameters. The simulation was used to solve two kinds of virtual blood vessel models: the ideal and realistic stenotic models. The simulation results in pressure estimation along the ideal stenotic model range of 0,012 – 0,026 MPa, depending on the BA configuration. Therefore, the maximum pressure obtained is 0,245 MPa in a realistic model. Both models’ pressure estimations are below the BA’s Rated Burst Pressure (RBP). On the other hand, CFD results in maximum pressure at 0,488 Pa and maximum Wall Shear Stress (WSS) at 0,92 Pa. The simulation results could be a recommendation for medical personnel to choose the best BA and stent best configuration to treat specific stenosis cases.