SIMULTANEOUS COCRYSTALLIZATION AND MICRONIZATION OF PARACETAMOL-DIPICOLINIC ACID BY SUPERCRITICAL ANTISOLVENT (SAS)
Paracetamol (PCA) is the widely used analgesic and antipyretic drug. In the market, PCA exist as polymorph form I which have poor tabletability. The aim of this study was to improve the tabletability of PCA by using cocrystallization method with dipicolinic acid (DPA) and to evaluate the influence o...
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Format: | Theses |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/78630 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |