#TITLE_ALTERNATIVE#
Abstract: <br /> <br /> <br /> Aqueous extracts of the leaves of Jatropha Curcas L(Euphorbiaceae) in graded doses have been investigated in anaesthesized male adult rats of the strain Wistar. <br /> <br /> <br /> Intravenous administration was found to induce a...
Saved in:
| Main Author: | |
|---|---|
| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/8441 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | Abstract: <br />
<br />
<br />
Aqueous extracts of the leaves of Jatropha Curcas L(Euphorbiaceae) in graded doses have been investigated in anaesthesized male adult rats of the strain Wistar. <br />
<br />
<br />
Intravenous administration was found to induce a prompt fall in arterial blood pressure of short duration, in a dose related fashion an interfal of 5 - 10 minutes was maintained betwen two successive extract administration. This hipotensive effect was not modified by atropini or propanolol pretreatment. At the dose of 100 mg/kg body weight, Jatropha extract reduced the respon of adrenalin, noradrenalin and tyramin in doses of respectively 2, 2, 200 mcg/kg body weight (0C adrenergik reseptor inhibition). <br />
<br />
<br />
Interaction with yohimbin (0L-adrenolytic) reveales that the extract prolonged the duration of its effect, suggesting that the hypotensive effect of Jatropha curcas L is likely to be mediated via oC adrenolytic mechanism. <br />
|
|---|