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Abstract: <br /> <br /> <br /> The local anaesthetic effect of lidocaine-epinephrine preparations administered by iontophoresis has been studied on rabbits. <br /> <br /> <br /> The evaluation of the anaesthetic effect was done by the prick test and by intermitt...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/8464 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |
| Summary: | Abstract: <br />
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The local anaesthetic effect of lidocaine-epinephrine preparations administered by iontophoresis has been studied on rabbits. <br />
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The evaluation of the anaesthetic effect was done by the prick test and by intermittent electric current test. A strong relation between the two methods was found (the corelation factor of each treatment is between 0,84-0,99). <br />
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A comparison between two products (factory made and the other one prepared in the laboratory) with the same concentration of lidocaine and different salts of epinephrine resulted in a meaningful difference of anesthesia (P<0,05), the one prepared in the laboratory having the greater effect. <br />
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The effect of local anaesthesia produce by subcutan injection was much greater (more than three hours) compare to the one produce by iontophoresis (less than one hour). <br />
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Among the various lidocaine-epinephrine preparations studied in this experiment for their local anaesthetic effect, the greatest effect was observed with the preparation containing lidocaine HCl 2% and epinephrine bitartrat 1:80.000. |
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