POTENCY OF IODINATED 5,10,15,20-TETRAKIS(4-AMINOPHENYL) PORPHYRIN AS RADIOPHARMACEUTICALS FOR CHRONIC MYELOID LEUKEMIA: IN SILICO STUDY

5,10,15,20-tetrakis(4-aminophenyl) porphyrin (TAPP) is a porphyrin derivative with potential as a radiopharmaceutical ligand. TAPP labeled with the radionuclide Iodine-131 can be used as an anticancer agent targeting BCR-ABL1 and BRD4 oncoproteins. BCR-ABL1 is involved in the pathology of Chronic...

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Bibliographic Details
Main Author: Kurniawan, Michael
Format: Theses
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/85364
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Institution: Institut Teknologi Bandung
Language: Indonesia