POTENCY OF IODINATED 5,10,15,20-TETRAKIS(4-AMINOPHENYL) PORPHYRIN AS RADIOPHARMACEUTICALS FOR CHRONIC MYELOID LEUKEMIA: IN SILICO STUDY
5,10,15,20-tetrakis(4-aminophenyl) porphyrin (TAPP) is a porphyrin derivative with potential as a radiopharmaceutical ligand. TAPP labeled with the radionuclide Iodine-131 can be used as an anticancer agent targeting BCR-ABL1 and BRD4 oncoproteins. BCR-ABL1 is involved in the pathology of Chronic...
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Format: | Theses |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/85364 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |