Antiplasmodial decarboxyportentol acetate and 3,4-dehydrotheaspirone from Laumoniera bruceadelpha

Antiplasmodial decarboxyportentol acetate and 3,4-dehydrotheaspirone from Laumoniera bruceadelpha

A new spiro heterocycle, decarboxyportentol acetate (1) was isolated from the barks of Laumoniera bruceadelpha Nooteboom (Simaroubaceae), together with 3,4-dehydrotheaspirone (2), and their structures were elucidated by 2D NMR analysis. 3,4-Dehydrotheaspirone (2) showed potent antiplasmodial activit...

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Bibliographic Details
Main Authors: Hiroshi Morita, -, Reika Mori, -, Jun Deguchi, -, Shiori Oshimi, -, Yusuke Hirasawa, -, Wiwied Ekasari, -, Aty Widyawaruyanti, -, A. Hamid A. Hadi, -
Format: Article PeerReviewed
Language:English
English
English
Published: Springer Verlag 2012
Subjects:
R Medicine
RS Pharmacy and materia medica
RS1-441 Pharmacy and materia medica
RS200-201 Pharmaceutical dosage forms
Online Access:https://repository.unair.ac.id/100939/1/C-14_artikel.pdf
https://repository.unair.ac.id/100939/2/C-14_penilaian%20kualitas%20karil.pdf
https://repository.unair.ac.id/100939/3/C-14_similarity.pdf
https://repository.unair.ac.id/100939/
https://link.springer.com/article/10.1007/s11418-011-0618-7
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Institution: Universitas Airlangga
Language: English
English
English
Description
Summary:A new spiro heterocycle, decarboxyportentol acetate (1) was isolated from the barks of Laumoniera bruceadelpha Nooteboom (Simaroubaceae), together with 3,4-dehydrotheaspirone (2), and their structures were elucidated by 2D NMR analysis. 3,4-Dehydrotheaspirone (2) showed potent antiplasmodial activity against Plasmodium falciparum 3D7.

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