Formulation of Metformin-Loaded Alginate Microspheres by Ionotropic Gelation-Aerosolization Technique

• Main Authors: Dewi Melani Hariyadi, Yashwant Pathak, Esti Hendradi, Tristiana Erawati, Izzatul Hidayah, Elizabeth Santos
• Format: Article PeerReviewed
• Language: English; English; English; English; English; English; English; English; English; English
• Published: Universiti Kebangsaan Malaysia 2020
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/103925/1/C-02%20FULLTEXT.pdf; http://repository.unair.ac.id/103925/2/Validasi%20C-02%20tambahan-DM.pdf; http://repository.unair.ac.id/103925/3/C-02%20Result.pdf; http://repository.unair.ac.id/103925/4/C-2.pdf; http://repository.unair.ac.id/103925/9/C-04Tambahan%20Validasi%20baru%281%29-ES-tt.pdf; http://repository.unair.ac.id/103925/10/C-4.pdf; http://repository.unair.ac.id/103925/11/C-04%20Result.pdf; http://repository.unair.ac.id/103925/15/C-01%20Fulltext.pdf; http://repository.unair.ac.id/103925/16/C-01%20Peer%20Review.pdf; http://repository.unair.ac.id/103925/17/C-01%20Similarity.pdf; http://repository.unair.ac.id/103925/; http://www.ukm.my/jsm/english_journals/vol49num10_2020/vol49num10_2020pg2513-2525.html; http://www.ukm.my/jsm/pdf_files/SM-PDF-49-10-2020/17.pdf
• Institution: Universitas Airlangga

Metformin hydrochloric acid (HCl)-loaded alginate microspheres prepared using aerosolization method were subsequently evaluated for their physico-chemical characteristics in terms of particle size, morphology, drug loading, entrapment efficiency, yield and in vitro release. A two factorial Design of...