Influence of drug-polymer ratio on physical characteristics and release of metformin hydrochloride from metforminalginate microspheres

• Main Authors: Dewi Melani Hariyadi, Esti Hendradi, Tristiana Erawati, EDLIN NUR JANNAH, WENNY FEBRINA
• Format: Article PeerReviewed
• Language: English; English; English; English; English; English; English; English; English; English
• Published: Pharmacotherapy Group Faculty of Pharmacy University of Benin, Benin City Nigeria 2018
• Subjects: R Medicine; RS Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/86213/8/C-6%20fix.pdf; http://repository.unair.ac.id/86213/1/Result%20Bukti%20C-06.pdf; http://repository.unair.ac.id/86213/15/C-06%20Reviewer.pdf; http://repository.unair.ac.id/86213/9/C2%20fix.pdf; http://repository.unair.ac.id/86213/3/C-02%20Influence%20of%20drug-polymer%20ratio%20on%20physical%20characteristics%20and%20release%20of%20metformin%20hydrochloride%20from%20metformin-alginate%20microspheres.pdf; http://repository.unair.ac.id/86213/14/C-02%20Reviewer.pdf; http://repository.unair.ac.id/86213/10/Artikle%20C-4.pdf; http://repository.unair.ac.id/86213/11/C-04%20Result%20-%20Influence%20of%20drug-polymer%20ratio.pdf; http://repository.unair.ac.id/86213/16/C-04%20Reviewer.pdf; http://repository.unair.ac.id/86213/17/Korespondensi%20GB2020%20C-2.pdf; http://repository.unair.ac.id/86213/; https://www.tjpr.org/admin/12389900798187/2018_17_7_1.pdf
• Institution: Universitas Airlangga

Purpose: To investigate the effect of drug and polymer ratio on the physical characteristics and release rate of metformin hydrochloride from alginate microspheres. Methods: Microspheres were prepared by ionotropic gelation aerosolization technique using sodium alginate as polymer and calcium chlori...