Antifibrotic Effects of Limbal Mesenchymal Stem Cells-Conditioned Media (LMSCs-CM) on Human Tenon’s Fibroblasts (HTFs) in Glaucomatous Eyes: Comparison with Mitomycin C

• Main Authors: Evelyn Komaratih, Yuyun Rindiastuti, Helen Susilowati, Nurita Tri Wijayanti, Sylva Dranindi, Yulia Primitasari, Nurwasis, Widya Artini, Fedik Abdul Rantam, Cita Rosita Sigit Prakoeswa
• Format: Article PeerReviewed
• Language: English; English; English; English
• Published: SAS Publishers 2019
• Subjects: R Medicine (General); RE Ophthalmology
• Online Access: http://repository.unair.ac.id/104163/1/Antifibrotic%20effects%20of%20limbal%20mesenchymal%20stem%20cells-conditioned%20media%20%28LMSCs-CM%29%20on%20Human%20Tenon%27s%20fibrobalsts%20%28HTFs%29%20in%20Glaucomatous%20eyes%20comparison%20with%20mitomycin%20C.pdf; http://repository.unair.ac.id/104163/2/Antifibrotic%20effect.pdf; http://repository.unair.ac.id/104163/5/Antifibrotic%20Effects%20of%20Limbal%20Mesenchymal%20Stem%20Cells-Conditioned%20Media.pdf; http://repository.unair.ac.id/104163/6/Antifibrotic%20effects.pdf; http://repository.unair.ac.id/104163/; https://pdfs.semanticscholar.org/a706/5bca26b2d002bd862086e9aba6339a8fbb04.pdf?_ga=2.26393211.753308604.1613546923-803857883.1598715832
• Institution: Universitas Airlangga

Human tenon‘s fibroblasts (HTFs) is the key effector of bleb fibrosis after trabeculectomy. Excessive fibroblast proliferation and differentiation into myofibroblast contribute to disturbance of extracellular matrix remodeling, result in irreversible fibrosis. In this study we investigated the effec...