Fibrin Glue (FG) Attenuates Fibrosis On Human Tenon's Fibroblasts (HYFS) of Glaucomatous Eyes : Comparison with Mitomycin C

• Main Authors: Yuyun Rindiastuti, Evelyn Komaratih, Helen Susilowati, Hendrian Dwikoloso Soebagjo, Fedik Abdul Rantam
• Format: Article PeerReviewed
• Language: English; English; English
• Published: DR. P. R. YADAV 2019
• Subjects: R Medicine (General); RE Ophthalmology
• Online Access: http://repository.unair.ac.id/95204/3/Fibrin%20Glue%20%28FG%29%20Attenuates%20Fibrosis%20on%20Human%20Tenons%20Fibroblasts%20%28HTFS%29%20of%20Glaucomatous%20Eyes%20Comparison%20With%20Mitomycin%20C.pdf; http://repository.unair.ac.id/95204/2/Fibrin%20Glue.pdf; http://repository.unair.ac.id/95204/4/Fibrin%20Glue%20%28FG%29%20Attenuates%20Fibrosis%20on%20Human%20Tenons%20Fibroblasts%20%28HTFS%29%20of%20Glaucomatous%20Eyes%20Comparison%20With%20Mitomycin%20C.pdf; http://repository.unair.ac.id/95204/; http://www.connectjournals.com/toc2.php?abstract=3066200H_4713A.pdf&&bookmark=CJ-033216&&issue_id=Supp-02&&yaer=2019
• Institution: Universitas Airlangga

Human tenon’s fibroblasts (HTFs) are major cells that contribute to the fibrotic response that usually occurs after trabeculectomy. The activation of HTFs into myofibroblast contributes to the disturbance of the extracellular matrix (ECM) remodeling. Excessive ECM deposition, mainly collagen type I,...