A New Cinnamyl Acid Derivative from the Roots of Willughbeia coriacea Wall
A new cinnamyl acid derivative, willughbein A (1) along with pinoresinol (2), alyterinate A (3), and scopoletin (4), were isolated from the roots of Willughbeia coriacea Wall. The structure of 1 has been determined based on HRESIMS, 1D, and 2D NMR spectral data. All of the isolates were evaluated fo...
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| Main Authors: | , , , , |
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| Format: | Article PeerReviewed |
| Language: | English English English English |
| Published: |
Korean Society of Pharmacognosy
2020
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/105810/3/C04.%20Fulltext_Willughbeia%20coriceae.pdf http://repository.unair.ac.id/105810/4/C04.%20Validasi%20dan%20Penilaian.pdf http://repository.unair.ac.id/105810/2/C04.%20Similarity_A%20New%20Cinnamyl%20Acid.pdf http://repository.unair.ac.id/105810/1/C04.%20Korespondensi.pdf http://repository.unair.ac.id/105810/ https://koreascience.or.kr/article/JAKO202010060596208.page https://doi.org/10.20307/nps.2020.26.1.79 |
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| Institution: | Universitas Airlangga |
| Language: | English English English English |
| Summary: | A new cinnamyl acid derivative, willughbein A (1) along with pinoresinol (2), alyterinate A (3), and scopoletin (4), were isolated from the roots of Willughbeia coriacea Wall. The structure of 1 has been determined based on HRESIMS, 1D, and 2D NMR spectral data. All of the isolates were evaluated for their cytotoxicity against three human cancer cells (HeLa, T47D, MCF-7, and P-388). Compound 3 showed moderate activity against P-388 cells with an IC50 value of 3.04 ㎍/mL. |
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