VLADINOL F, NEOLIGNAN COMPOUND FROM THE STEM BARK OF Dryobalanops oblongifolia (DIPTEROCARPACEAE) AND ANTIPLASMODIAL ACTIVITY
Drybalanops oblongifolia known as kayu kapur is a plant member of Dipterocarpaceae family. A neolignan, vladinol F, was successfully isolated from the dissolved fraction in acetone-ether of Dryobalanops oblongifolia stem bark. The chemical structure's determination was done based on an analysis...
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| Main Authors: | , , , , |
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| Format: | Article PeerReviewed |
| Language: | English English English English |
| Published: |
Rasayan Journal
2021
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/109930/2/C05.%20Fulltext_VLADINOL%20F_RASAYAN%20INDRI.pdf http://repository.unair.ac.id/109930/4/C05.%20Review%20dan%20Validasi_VLADINOL%20F_RASAYAN%20INDRI.pdf http://repository.unair.ac.id/109930/1/C05.%20Similarity_25_VLADINOL%20F_RASAYAN%20INDRI.pdf http://repository.unair.ac.id/109930/3/C05.%20Bukti%20Komunikasi_VLADINOL%20F_RASAYAN%20INDRI.pdf http://repository.unair.ac.id/109930/ http://rasayanjournal.co.in/admin/php/upload/3051_pdf.pdf https://dx.doi.org/10.31788/%20RJC.2021.1416017 |
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| Institution: | Universitas Airlangga |
| Language: | English English English English |
| Summary: | Drybalanops oblongifolia known as kayu kapur is a plant member of Dipterocarpaceae family. A neolignan, vladinol F, was successfully isolated from the dissolved fraction in acetone-ether of Dryobalanops oblongifolia stem bark. The chemical structure's determination was done based on an analysis of UV-Vis, NMR, and MS spectra and a comparison with the reference. In vitro test of this compound against Plasmodium falciparum 3D7 showed that IC50 value was 3.51 μg/mL. |
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