Correlation of Low CD4+ Counts with High Dental Caries Prevalence in Children Living with Perinatal HIV/AIDS Undergoing Antiretroviral Therapy
Objective: To investigate the correlation Cluster of Differentiation 4⁺ (CD4⁺) counts with a high prevalence of dental caries in Children Living with Perinatal Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (CLWPHA). Material and Methods: An analytical observational research with a...
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| Main Authors: | , , , , , , |
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| Format: | Article PeerReviewed |
| Language: | English English English |
| Published: |
Associacao de Apoio a PesquisaemSaudeBucal - APESB
2019
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| Subjects: | |
| Online Access: | https://repository.unair.ac.id/114486/2/C15-Similarity.pdf https://repository.unair.ac.id/114486/4/C15-Artikel.pdf https://repository.unair.ac.id/114486/7/C15-Peer%20Review.pdf https://repository.unair.ac.id/114486/ https://www.researchgate.net/publication/336211778_Correlation_of_Low_CD4_Counts_with_High_Dental_Caries_Prevalence_in_Children_Living_with_Perinatal_HIVAIDS_Undergoing_Antiretroviral_Therapy http://dx.doi.org/10.4034/PBOCI.2019.191.119 |
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| Institution: | Universitas Airlangga |
| Language: | English English English |
| Summary: | Objective: To investigate the correlation Cluster of Differentiation 4⁺ (CD4⁺) counts with a high prevalence of dental caries in Children Living with Perinatal Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (CLWPHA). Material and Methods: An analytical observational research with a cross-sectional design was conducted at Tertiary General Hospital, Surabaya, Indonesia. Randomized total sampling consisted of 29 CLWPHA 1-12 years old at outpatient ward Infectious Disease Intermediate Unit (UPIPI) Tertiary General Hospital Doctor Soetomo Surabaya. Demographic details and recent CD4⁺ counts obtained from medical records. Decayed, missing, filled teeth (dmft) in primary teeth and DMFT in permanent teeth index were used. Pearson's and Spearman's Correlation test (p<0.05) were performed Results: Dental caries prevalence was 86.2%; meanwhile, the dmft/DMFT index score found were high (8.2 / 6.3). CD4⁺ count and caries showed significant correlation (r=-0.394, p<0.05). Tooth brushing frequency with caries showed a significant correlation (r=-0.419, p<0.05). Antiretroviral (ARV) therapy and caries showed an insignificant negative correlation (p<0.05) Conclusion: The high prevalence of dental caries in CLWPHA correlated with low CD4⁺ counts. |
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