A Woman with Tuberculosis Multidrug Resistance and QTc Prolongation Repetitive Interval: A Case Report
Abstract Background : Prolonged QTc interval is one of the side effects of the short-regimen MDR-TB. QTc prolongation is a risk factor for Torsades de pointes and is influenced by many factors. Case : 47-year-old woman who was diagnosed with MDR-TB through GeneXpert examination and received short...
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| Main Authors: | , , , , , |
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| Format: | Article PeerReviewed |
| Language: | English English Indonesian |
| Published: |
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| Online Access: | https://repository.unair.ac.id/120149/1/22%20artikel.pdf https://repository.unair.ac.id/120149/2/22%20turnitin.pdf https://repository.unair.ac.id/120149/3/22.%20A%20Woman%20with%20Tuberculosis.pdf https://repository.unair.ac.id/120149/ https://medicopublication.com/index.php/ijfmt/issue/view/88 https://doi.org/10.37506/ijfmt.v15i4 |
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| Institution: | Universitas Airlangga |
| Language: | English English Indonesian |
| Summary: | Abstract
Background : Prolonged QTc interval is one of the side effects of the short-regimen MDR-TB. QTc
prolongation is a risk factor for Torsades de pointes and is influenced by many factors. Case : 47-year-old
woman who was diagnosed with MDR-TB through GeneXpert examination and received short-regimen
MDR-TB. This patient experienced repeated QTc prolongation, with peak QTc interval 600 msec occurring
at 4th month with mild hypokalemia without clinical symptoms. The patient completed 9 months of shortregimen
therapy with improve chest x ray followed by negative sputum culture. Conclusion : Short-regimen
MDR-TB contains several drugs that cause QTc prolongation. Clinical evaluation is required in patients
with QTc prolongation before changing the regiment. |
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