Sifat Antioksidan Bawang Putih (Allium Sativurn) Yang Berperan Sebagai Hepatoprotektor Pada Tikus Putih (Rattus Norvegicus Galur Sprague Dawley) Yang Diinduksi Dengan Cci4
This study was aimed to identify the role of garlic as antioxidant and hepatoprotector on CCI4-induced rat. Experimental laboratory method was used in this study. Three different treatments (garlic extract of 2.5 g/kg bw, 5 g/kg bw, and 10 glkg bw) were given everyday for 8 days. Two control, negat...
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| Main Author: | |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | Indonesian |
| Published: |
2001
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| Online Access: | https://repository.unair.ac.id/120861/1/KKB%20KK%20TKD%2024-01%20Hid%20S.pdf https://repository.unair.ac.id/120861/ http://www.lib.unair.ac.id |
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| Institution: | Universitas Airlangga |
| Language: | Indonesian |
| Summary: | This study was aimed to identify the role of garlic as antioxidant and hepatoprotector on CCI4-induced rat.
Experimental laboratory method was used in this study. Three different treatments (garlic extract of 2.5 g/kg bw, 5 g/kg bw, and 10 glkg bw) were given everyday for 8 days. Two control, negative and positive, were used for comparison. MDA (malondialdehyde) examination was performed using TBA (thiobarbituric acid) test, serum GPT (glutamate pyruvate transaminase ) , and histopathological examination.
Results showed that garlic administration of 10 g/kg bw could prevent the increase of MDA concentration, the occurrence of centrilobular necrosis, and the increase of GPT concentration. It indicated that garlic dose of 10 g/kg bw had antioxidant and hepatoprotective activity on CCI4-induced rat. |
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