Effect of Intravenous Glutamine on Caspase-12 Expression in the Apoptosis of the Glomerular Epithelial Cells of Male Rats Exposed to Cisplatin

• Main Authors: Tamara Aulia Fakhrinnisa, Tamara, Imam Susilo, Imam, Arifa Mustika, Arifa, Miyayu Soneta Sofyan, Miyayu
• Format: Article PeerReviewed
• Language: English; English; Indonesian; English; English
• Published: 1513-7368
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/124170/1/02.%20artikel.pdf; https://repository.unair.ac.id/124170/2/02.%20Effect%20of.pdf; https://repository.unair.ac.id/124170/3/2karil.pdf; https://repository.unair.ac.id/124170/4/02.%20Turnitin.pdf; https://repository.unair.ac.id/124170/9/Etik%20Effect%20of%20Intravenous.pdf; https://repository.unair.ac.id/124170/; http://journal.waocp.org/article_89474.html
• Institution: Universitas Airlangga

Abstract Objective: Cisplatin is potent chemotherapy for broad-spectrum malignancies treatment, but its use is limited by organ toxicity effects, including nephrotoxicity. Glutamine prevents cisplatin nephrotoxicity by inhibiting the oxidative stress in kidney cell apoptosis. Methods: This resea...