The effect of intravenous glutamine on the protein expression changes, caspase-12 and apoptosis in renal tubulus russ male, rattusnovergicusstrain wistar, exposed by cisplastin

• Main Authors: Yunitati Sutandio, Yunitati, Imam Susilo, Imam, Endang Joewarini, Endang
• Format: Article PeerReviewed
• Language: English; English; Indonesian; English; Indonesian
• Published: Universidad Tecnica de Manabi
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/124184/1/14.%20artikel.pdf; https://repository.unair.ac.id/124184/2/14.%20The%20effect%20of%20intravenous%20glutamine.pdf; https://repository.unair.ac.id/124184/3/14karil.pdf; https://repository.unair.ac.id/124184/6/14.%20Turnitin.pdf; https://repository.unair.ac.id/124184/8/5%20etik.pdf; https://repository.unair.ac.id/124184/; https://sciencescholar.us/journal/index.php/ijhs/article/view/11375; https://doi.org/10.53730/ijhs.v6nS4.11375
• Institution: Universitas Airlangga

ABSTRACT Cisplatin efficacy is dependent on dose. The cisplatin-induced apoptosis pathway can go through the ER stress pathway which will activate Bax and Bak (proapoptosis) causing calcium homeostasis disorders to occur. Glutamine protective effect on caspase-12 expression on the prevention of apo...