Effect of Probiotic Milk containing L. casei Shirota on Immunoglobulin G Levels among Anemic Adolescent Girls

• Main Authors: Elya Sugianti, -, Annis Catur Adi, -, Ikeu Ekayanti, -, Trias Mahmudiono, -, Widati Fatmaningrum, Widati, Siti Nur Husnul Yusmiati, -
• Format: Article PeerReviewed
• Language: English; Indonesian; English
• Published: Humanistic Network for Science and Technology
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/126503/1/28.%20Artikel.pdf; https://repository.unair.ac.id/126503/2/28.%20Karil.pdf; https://repository.unair.ac.id/126503/3/28.%20Turnitin.pdf; https://repository.unair.ac.id/126503/; http://heanoti.com/index.php/hn/article/view/hn20227; https://doi.org/10.33846/hn.v2i2.138
• Institution: Universitas Airlangga

ABSTRACT Probiotic play important role on immune systems. This study was to investigate effect of probiotic milk containing L. casei Shirota on immunoglobulin G levels among anemic adolescent girls. A total of 22 adolescent girls aged 13-18 years with anemia were included on this study. The subjects were separated into 2 groups i.e. a probiotic group and a control group by simple random sampling. During 4 weeks, a probiotic group received 1 tablet of 60 Fe elemental + 250 µg folate acid once a week and probiotic milk once daily. While a control group received 1 tablet of 60 Fe elemental + 250 µg folate acid once a week. Blood samples were collected at 0 and 4 weeks and assayed for immunoglobulin G levels by ELISA. Immunoglobulin G levels were not significantly increase after intervention. Compared with control group, probiotic milk administration in probiotic group did not significantly increased immunoglobulin G levels (p>0.05). The probiotic milk containing L. casei Shirota did not improve immunoglobulin G levels on anemic adolescent girls.