Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia
Abstract: Chronic myeloid leukemia (CML) is a type of myeloproliferative neoplasm (MPN) in which granulocytes are the primary proliferating cells. CML in pediatric patients (juvenile CML) is an uncommon MPN, representing 2–3% of children newly diagnosed with leukemia. Sensorineural hearing loss th...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article PeerReviewed |
| Language: | English English English |
| Published: |
2022
|
| Subjects: | |
| Online Access: | https://repository.unair.ac.id/127516/1/jurnal%20Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf https://repository.unair.ac.id/127516/2/karil%20Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf https://repository.unair.ac.id/127516/3/Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf https://repository.unair.ac.id/127516/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Universitas Airlangga |
| Language: | English English English |
| Summary: | Abstract: Chronic myeloid leukemia (CML) is a type of myeloproliferative neoplasm (MPN) in which granulocytes are the primary
proliferating cells. CML in pediatric patients (juvenile CML) is an uncommon MPN, representing 2–3% of children newly diagnosed
with leukemia. Sensorineural hearing loss that progresses rapidly is an uncommon early sign of a hematological disorder in patients
with CML. This article presents the case of a 10-year-old patient with complaints of bilateral hearing loss for 2 weeks. Pure-tone
audiometry indicated sensorineural hearing loss of the left ear and mixed hearing loss of the right ear. After an in-depth evaluation of a
bone marrow smear and positivity for the BCR-ABL fusion gene, it was concluded that the patient had chronic-phase juvenile CML.
However, hearing loss recovery after hydroxyurea therapy could not be observed because the patient died after suffering an
uncontrolled seizure on day 14 of hospitalization. |
|---|