Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia
Abstract: Chronic myeloid leukemia (CML) is a type of myeloproliferative neoplasm (MPN) in which granulocytes are the primary proliferating cells. CML in pediatric patients (juvenile CML) is an uncommon MPN, representing 2–3% of children newly diagnosed with leukemia. Sensorineural hearing loss th...
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id-langga.1275162023-06-22T12:45:47Z https://repository.unair.ac.id/127516/ Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia Ihda Kartika Syamsuddin Paulus Budiono Notopuro RB Pathology Abstract: Chronic myeloid leukemia (CML) is a type of myeloproliferative neoplasm (MPN) in which granulocytes are the primary proliferating cells. CML in pediatric patients (juvenile CML) is an uncommon MPN, representing 2–3% of children newly diagnosed with leukemia. Sensorineural hearing loss that progresses rapidly is an uncommon early sign of a hematological disorder in patients with CML. This article presents the case of a 10-year-old patient with complaints of bilateral hearing loss for 2 weeks. Pure-tone audiometry indicated sensorineural hearing loss of the left ear and mixed hearing loss of the right ear. After an in-depth evaluation of a bone marrow smear and positivity for the BCR-ABL fusion gene, it was concluded that the patient had chronic-phase juvenile CML. However, hearing loss recovery after hydroxyurea therapy could not be observed because the patient died after suffering an uncontrolled seizure on day 14 of hospitalization. 2022 Article PeerReviewed text en https://repository.unair.ac.id/127516/1/jurnal%20Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf text en https://repository.unair.ac.id/127516/2/karil%20Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf text en https://repository.unair.ac.id/127516/3/Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf Ihda Kartika Syamsuddin and Paulus Budiono Notopuro (2022) Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia. International Medical Case Reports Journal, 22 (15). pp. 367-371. ISSN 1179142X |
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RB Pathology Ihda Kartika Syamsuddin Paulus Budiono Notopuro Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia |
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Abstract: Chronic myeloid leukemia (CML) is a type of myeloproliferative neoplasm (MPN) in which granulocytes are the primary
proliferating cells. CML in pediatric patients (juvenile CML) is an uncommon MPN, representing 2–3% of children newly diagnosed
with leukemia. Sensorineural hearing loss that progresses rapidly is an uncommon early sign of a hematological disorder in patients
with CML. This article presents the case of a 10-year-old patient with complaints of bilateral hearing loss for 2 weeks. Pure-tone
audiometry indicated sensorineural hearing loss of the left ear and mixed hearing loss of the right ear. After an in-depth evaluation of a
bone marrow smear and positivity for the BCR-ABL fusion gene, it was concluded that the patient had chronic-phase juvenile CML.
However, hearing loss recovery after hydroxyurea therapy could not be observed because the patient died after suffering an
uncontrolled seizure on day 14 of hospitalization. |
format |
Article PeerReviewed |
author |
Ihda Kartika Syamsuddin Paulus Budiono Notopuro |
author_facet |
Ihda Kartika Syamsuddin Paulus Budiono Notopuro |
author_sort |
Ihda Kartika Syamsuddin |
title |
Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia |
title_short |
Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia |
title_full |
Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia |
title_fullStr |
Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia |
title_full_unstemmed |
Sensorineural Hearing Loss in Juvenile CML:A Rare Case Report in Surabaya, Indonesia |
title_sort |
sensorineural hearing loss in juvenile cml:a rare case report in surabaya, indonesia |
publishDate |
2022 |
url |
https://repository.unair.ac.id/127516/1/jurnal%20Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf https://repository.unair.ac.id/127516/2/karil%20Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf https://repository.unair.ac.id/127516/3/Sensorineural%20Hearing%20Loss%20in%20Juvenile%20CML.pdf https://repository.unair.ac.id/127516/ |
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