EFEK PROTEKTIF ALUMINIUM SILIKAT TERHADAP KUALITAS SPERMATOZOA, INTEGRITAS MEMBRAN PLASMA DAN GAMBARAN HISTOPATOLOGI TUBULUS SEMINIFERUS YANG DIINDUKSI FUSARIUM GRAMINEARUM PADA MENCIT JANTAN (Mus musculus)
Fusarium graminearum is a estrogenic fungal pathogen that produce zearalenon and deoxynivalenol mycotoxins cause of infertility in reproductive organs. This study was using 20 adult male mice were divided into 5 groups that treated for 21 days. All groups were given treatment per oral with sonde...
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| Format: | Theses and Dissertations NonPeerReviewed |
| Language: | English English |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/61370/1/abstrak.pdf http://repository.unair.ac.id/61370/2/TESIS%20SONDANG%20LENGKAP%20JADI.compressed.pdf http://repository.unair.ac.id/61370/ |
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| Institution: | Universitas Airlangga |
| Language: | English English |
| Summary: | Fusarium graminearum is a estrogenic fungal pathogen that produce
zearalenon and deoxynivalenol mycotoxins cause of infertility in reproductive
organs. This study was using 20 adult male mice were divided into 5 groups that
treated for 21 days. All groups were given treatment per oral with sonde for 21
days. K- as negative control weren’t treated F.graminearum and aluminium
silicate, K+ as positive control were treated with F.graminearum, P1 were treated
with F.graminearum 0,25ml/mice/day and aluminium silicate 0,5 mg/mice/day,
P2 were treated with F.graminearum 0,25ml/mice/day and aluminium silicate
1mg/mice/day and P3 were treated with F.graminearum 0,25ml/mice/day and
aluminium silicate 2mg/mice/day. The data was analyzed by ANOVA followed
by Fisher's LSD and Duncan.The results showed that the K- significantly
different (p <0.05) with K +, P1, P2 to P3 while K- not significantly different (p>
0.05) on motility. At the viability of spermatozoa K- significantly different (p
<0.05) with K +, P1, P2 and P3, while K + significantly different (p <0.05) with
K, P1, P2 and treatment P1, P2 and P3 were not significantly different (p> 0.05).
K + results were significantly different (p <0.05) with K, P1, P2 and P3, while
K-, P1, P2 and P3 were not significantly different (p> 0.05) on sperm
abnormalities. Significant differences (p <0.05) between the treatment groups
except between K-P3 is not significantly different (P> 0.05) in the percentage of
plasma membrane integrity. On seminiferous tubulesscoring an increase of
behavioral p1, p2 and p3 is 8.1; 8.72 and 9.5. The result showed that treated with
aluminium silicate 2mg/mice/day was effective to eliminate Fusarium
graminearum induction. |
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