EFEK PROTEKTIF ALUMINIUM SILIKAT TERHADAP KUALITAS SPERMATOZOA, INTEGRITAS MEMBRAN PLASMA DAN GAMBARAN HISTOPATOLOGI TUBULUS SEMINIFERUS YANG DIINDUKSI FUSARIUM GRAMINEARUM PADA MENCIT JANTAN (Mus musculus)

• Main Author: SONDANG ONE MAYOSITA, 061414153002
• Format: Theses and Dissertations NonPeerReviewed
• Language: English; English
• Published: 2017
• Subjects: SF600-1100 Veterinary medicine
• Online Access: http://repository.unair.ac.id/61370/1/abstrak.pdf; http://repository.unair.ac.id/61370/2/TESIS%20SONDANG%20LENGKAP%20JADI.compressed.pdf; http://repository.unair.ac.id/61370/
• Institution: Universitas Airlangga

Fusarium graminearum is a estrogenic fungal pathogen that produce zearalenon and deoxynivalenol mycotoxins cause of infertility in reproductive organs. This study was using 20 adult male mice were divided into 5 groups that treated for 21 days. All groups were given treatment per oral with sonde for 21 days. K- as negative control weren’t treated F.graminearum and aluminium silicate, K+ as positive control were treated with F.graminearum, P1 were treated with F.graminearum 0,25ml/mice/day and aluminium silicate 0,5 mg/mice/day, P2 were treated with F.graminearum 0,25ml/mice/day and aluminium silicate 1mg/mice/day and P3 were treated with F.graminearum 0,25ml/mice/day and aluminium silicate 2mg/mice/day. The data was analyzed by ANOVA followed by Fisher's LSD and Duncan.The results showed that the K- significantly different (p <0.05) with K +, P1, P2 to P3 while K- not significantly different (p> 0.05) on motility. At the viability of spermatozoa K- significantly different (p <0.05) with K +, P1, P2 and P3, while K + significantly different (p <0.05) with K, P1, P2 and treatment P1, P2 and P3 were not significantly different (p> 0.05). K + results were significantly different (p <0.05) with K, P1, P2 and P3, while K-, P1, P2 and P3 were not significantly different (p> 0.05) on sperm abnormalities. Significant differences (p <0.05) between the treatment groups except between K-P3 is not significantly different (P> 0.05) in the percentage of plasma membrane integrity. On seminiferous tubulesscoring an increase of behavioral p1, p2 and p3 is 8.1; 8.72 and 9.5. The result showed that treated with aluminium silicate 2mg/mice/day was effective to eliminate Fusarium graminearum induction.