PENENTUAN KADAR GULA DARAH PADA PEMBERIAN SERBUK PORANG (Amorphophallus onchophyllus) DAN SERBUK KONJAK (Amorphophallus konjac) TERSTANDAR GLUKOMANAN PADA MENCIT PUTIH (Mus Musculus) YANG DIINDUKSI DENGAN ALOKSAN MONOHIDRAT

• Main Author: AMANDA EKA PERTIWI, 051311133138
• Format: Theses and Dissertations NonPeerReviewed
• Language: Indonesian; Indonesian
• Published: 2017
• Subjects: RS Pharmacy and materia medica
• Online Access: http://repository.unair.ac.id/65273/1/FF.KF.35.17%20.%20Per.p%20-%20ABSTRAK.pdf; http://repository.unair.ac.id/65273/2/FF.KF.35.17%20.%20Per.p%20-%20SEC.pdf; http://repository.unair.ac.id/65273/; http://lib.unair.ac.id
• Institution: Universitas Airlangga

Porang (Amorphophallus oncophyllus) and konjak (Amorphophallus konjac) is a type of tuber plant that contains glukomanan Polysaccharide, which glukomanan can be used to lower blood sugar levels. In this research is to know the effect of decreasing blood sugar level given by porang powder and konjak powder standard glucomannan. Glucomannan concentration in porang powder was 52,33 ± 0,74 % (w/w) and glucomannan content on konjak powder was 61,24 ± 0,61 % (w/w). The sample of this study wese eight group of mice as treatment groups with six replications on 2-2,5 months of male mice strain BALB/C which had been induced by alloxan monohydrate (200 mg/ kg body weight of mice). The treatment group consist of negative control (CMC sodium 0,3%), positive control (glibenclamide 0,013 mg / 20g body weight of mice), and treatment group I, II, III, IV, V, VI with the administration of porang powder standard glukomannan dose of 85; 165; 250 mg/ kg body weight of mice and konjak powder standard glukomannan dose of 85; 165; 250 mg/ kg Body weight of mice. Treatment is given daily for 21 days with measurement of blood glucose level every three days and weight every day. The result was analyzed by One Way ANOVA with significant value of 5%. The result indicated that konjak powder standard glucomannan dose of 250 mg / kg body weight of mice can decrease blood sugar level within 13 days.