The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of Porphyromonas gingivalis
Background : Periodontitis is an inflammation on periodontal structure that caused by invasion microorganism. Among periodontitis’s types, chronic periodontitis is the most prevalent type and often associated with Porphyromonas gingivalis. Nowadays, herbal therapy is often used as antibacterial a...
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| Main Authors: | , , |
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| Format: | Article PeerReviewed |
| Language: | English English English |
| Published: |
Fakultas Kedokteran Gigi Unair
2012
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| Subjects: | |
| Online Access: | http://repository.unair.ac.id/73243/2/PD-4-1-2012-01468-abs.pdf http://repository.unair.ac.id/73243/1/ernie%2022.pdf http://repository.unair.ac.id/73243/3/Daya%20Hambat%20Ekstrak%20Buah%20Mengkudu%20%28Morinda%20citrifolia%20L.%29%20Terhadap%20Pertumbuhan%20Bakteri%20Porphyromonas%20gingivalis.pdf http://repository.unair.ac.id/73243/ http://dentj.fkg.unair.ac.id/periodontic-journal-dept-7-vol-4-no-1.html |
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| Institution: | Universitas Airlangga |
| Language: | English English English |
| Summary: | Background : Periodontitis is an inflammation on periodontal structure that caused by invasion
microorganism. Among periodontitis’s types, chronic periodontitis is the most prevalent type and
often associated with Porphyromonas gingivalis. Nowadays, herbal therapy is often used as
antibacterial agent to inhibit microorganism’s growth. The herbs used in this research is noni fruit
extract (Morinda citrifolia L.) that contain many antibacterial agent such as anthraquinone, saponin,
and iridoid. Purpose : The aim of this research is to find the inhibition of noni fruit extract (Morinda
citrifolia L.) on the growth of Porphyromonas gingivalis. Method : This research was done in vitro
experiment using agar disc diffusion method. The extract was diluted into concentration of 100%,
50%, 25%, 12,5%, 6,25%, 3,12%, 1,56%, 0,78%, 0,39%, and 0,19%. The inhibitory zones were
recorded in millimeters and analyzed using One Way ANOVA test. Result : The result showed that
antibacterial activity of noni fruit extract was active on Porphyromonas gingivalis with Minimum
Inhibitory Concentration (MIC) of 3,12% with average of inhibitory zone 8,21 mm. From statistical
test showed that there were significant differences of inhibitory zone from each concentration.
Conclusion : Noni fruit extract (Morinda citrifolia L.) could inhibit the growth of Porphyromonas
gingivalis with Minimum Inhibitory Concentration (MIC) at 3,12%. |
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