The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of Porphyromonas gingivalis
Background : Periodontitis is an inflammation on periodontal structure that caused by invasion microorganism. Among periodontitis’s types, chronic periodontitis is the most prevalent type and often associated with Porphyromonas gingivalis. Nowadays, herbal therapy is often used as antibacterial a...
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id-langga.732432018-07-18T19:11:29Z http://repository.unair.ac.id/73243/ The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of Porphyromonas gingivalis Adam Widya, Wicaksono Ernie Maduratna, Setiawatie Mohamad Rubianto, Rubianto R Medicine RK Dentistry Background : Periodontitis is an inflammation on periodontal structure that caused by invasion microorganism. Among periodontitis’s types, chronic periodontitis is the most prevalent type and often associated with Porphyromonas gingivalis. Nowadays, herbal therapy is often used as antibacterial agent to inhibit microorganism’s growth. The herbs used in this research is noni fruit extract (Morinda citrifolia L.) that contain many antibacterial agent such as anthraquinone, saponin, and iridoid. Purpose : The aim of this research is to find the inhibition of noni fruit extract (Morinda citrifolia L.) on the growth of Porphyromonas gingivalis. Method : This research was done in vitro experiment using agar disc diffusion method. The extract was diluted into concentration of 100%, 50%, 25%, 12,5%, 6,25%, 3,12%, 1,56%, 0,78%, 0,39%, and 0,19%. The inhibitory zones were recorded in millimeters and analyzed using One Way ANOVA test. Result : The result showed that antibacterial activity of noni fruit extract was active on Porphyromonas gingivalis with Minimum Inhibitory Concentration (MIC) of 3,12% with average of inhibitory zone 8,21 mm. From statistical test showed that there were significant differences of inhibitory zone from each concentration. Conclusion : Noni fruit extract (Morinda citrifolia L.) could inhibit the growth of Porphyromonas gingivalis with Minimum Inhibitory Concentration (MIC) at 3,12%. Fakultas Kedokteran Gigi Unair 2012 Article PeerReviewed text en http://repository.unair.ac.id/73243/2/PD-4-1-2012-01468-abs.pdf text en http://repository.unair.ac.id/73243/1/ernie%2022.pdf text en http://repository.unair.ac.id/73243/3/Daya%20Hambat%20Ekstrak%20Buah%20Mengkudu%20%28Morinda%20citrifolia%20L.%29%20Terhadap%20Pertumbuhan%20Bakteri%20Porphyromonas%20gingivalis.pdf Adam Widya, Wicaksono and Ernie Maduratna, Setiawatie and Mohamad Rubianto, Rubianto (2012) The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of Porphyromonas gingivalis. Periodontic Journal, 4 (1). ISSN 2085-711X. http://dentj.fkg.unair.ac.id/periodontic-journal-dept-7-vol-4-no-1.html |
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R Medicine RK Dentistry Adam Widya, Wicaksono Ernie Maduratna, Setiawatie Mohamad Rubianto, Rubianto The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of Porphyromonas gingivalis |
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Background : Periodontitis is an inflammation on periodontal structure that caused by invasion
microorganism. Among periodontitis’s types, chronic periodontitis is the most prevalent type and
often associated with Porphyromonas gingivalis. Nowadays, herbal therapy is often used as
antibacterial agent to inhibit microorganism’s growth. The herbs used in this research is noni fruit
extract (Morinda citrifolia L.) that contain many antibacterial agent such as anthraquinone, saponin,
and iridoid. Purpose : The aim of this research is to find the inhibition of noni fruit extract (Morinda
citrifolia L.) on the growth of Porphyromonas gingivalis. Method : This research was done in vitro
experiment using agar disc diffusion method. The extract was diluted into concentration of 100%,
50%, 25%, 12,5%, 6,25%, 3,12%, 1,56%, 0,78%, 0,39%, and 0,19%. The inhibitory zones were
recorded in millimeters and analyzed using One Way ANOVA test. Result : The result showed that
antibacterial activity of noni fruit extract was active on Porphyromonas gingivalis with Minimum
Inhibitory Concentration (MIC) of 3,12% with average of inhibitory zone 8,21 mm. From statistical
test showed that there were significant differences of inhibitory zone from each concentration.
Conclusion : Noni fruit extract (Morinda citrifolia L.) could inhibit the growth of Porphyromonas
gingivalis with Minimum Inhibitory Concentration (MIC) at 3,12%. |
format |
Article PeerReviewed |
author |
Adam Widya, Wicaksono Ernie Maduratna, Setiawatie Mohamad Rubianto, Rubianto |
author_facet |
Adam Widya, Wicaksono Ernie Maduratna, Setiawatie Mohamad Rubianto, Rubianto |
author_sort |
Adam Widya, Wicaksono |
title |
The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of
Porphyromonas gingivalis |
title_short |
The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of
Porphyromonas gingivalis |
title_full |
The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of
Porphyromonas gingivalis |
title_fullStr |
The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of
Porphyromonas gingivalis |
title_full_unstemmed |
The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of
Porphyromonas gingivalis |
title_sort |
inhibition of noni fruit extract (morinda citrifolia l.) on the growth of
porphyromonas gingivalis |
publisher |
Fakultas Kedokteran Gigi Unair |
publishDate |
2012 |
url |
http://repository.unair.ac.id/73243/2/PD-4-1-2012-01468-abs.pdf http://repository.unair.ac.id/73243/1/ernie%2022.pdf http://repository.unair.ac.id/73243/3/Daya%20Hambat%20Ekstrak%20Buah%20Mengkudu%20%28Morinda%20citrifolia%20L.%29%20Terhadap%20Pertumbuhan%20Bakteri%20Porphyromonas%20gingivalis.pdf http://repository.unair.ac.id/73243/ http://dentj.fkg.unair.ac.id/periodontic-journal-dept-7-vol-4-no-1.html |
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