Anti Oxidant Activities of minocyclin in the saliva of chronic periodontitis patient using DPPH Assay

• Main Authors: ERNIE MADURATNA, 099611183M, Noer Ulfah, Ulfah
• Format: Conference or Workshop Item PeerReviewed
• Language: English; English
• Published: 2011
• Subjects: R Medicine; RK Dentistry
• Online Access: http://repository.unair.ac.id/73310/2/The%209th%20APS%20of%20Periodontology%20Hongkong.%20Anti%20Oxidant%20activities%20............pdf; http://repository.unair.ac.id/73310/1/ernie%2033.pdf; http://repository.unair.ac.id/73310/
• Institution: Universitas Airlangga

The saliva of chronic periodontitis patients will be oxidative stress due to increase risk breakdown of Dl A gingival epithelium . The mechanism of DNA breaks are present from vari et ies source, such as lipid perox idati on, ox idation of proteins and potential enzymes and the loss of pro inflamation cytokine. Minocycline was a second generation tetracyclines known to present several other effects, which are independent from their anti microbial activit ies. Minocycline demonstrated anti oxidant effect with radical scavenging activity comparable with alfa tocopherol. Minocycline be longing to the class of phenolic antioxidant.