Activation of innate immunity through toll-like receptor-2 by lipoteichoic acid bacteria entercoccus faecalis

• Main Author: Tamara Yuanita, NIDN. 0025066005
• Format: Conference or Workshop Item PeerReviewed
• Language: English; Indonesian
• Published: 2012
• Subjects: R Medicine; RK Dentistry
• Online Access: http://repository.unair.ac.id/84510/2/Tamara%20Prosiding%20Avtivation.pdf; http://repository.unair.ac.id/84510/3/Tamara%20per%2016.pdf; http://repository.unair.ac.id/84510/
• Institution: Universitas Airlangga

A persistent infection after root canal preparation is the main etiology in root canal treatment failure. Cleanup the complete of root canal preparation is difficult to achieve because of the complexity of root canal anatomy. The bacteria Enterococcus faecalis (E.Faecalis) is the largest species found In root canal treatment failure. Prevalence in the re-treatment amounting to 89.6% and 67.5% for primary infection. lipoteichoic acid ILTA) is a molecule found In Gram-positive bacterial cell surface that is functionally an important factor for growth and survival of bacteria. TLR-2 is a receptor expressed on the cell surface that recognize foreign substances such as bacteria. The conclusion of this paper is the destruction of microbes that cause infections is of paramount Importance to prevent re-infection. E.Faecalis is a bacteria that is resistant to root canal treatment procedures so that it can be a cause of failure of root canal treatment through the mechanisms of innate immunity activation of TLR-2 by LTA bacterium E.Faecalis.