EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL
This research aims was to observe liver histopathological features of mice toward the effect of Moringa oleifera leaves extract to reduce the damage of paracetamol administration. This research used 30 male mice aged 2-3 months with an average body weight of 20-30 grams and using completely rando...
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Online Access: | http://repository.unair.ac.id/89467/1/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Abstrak.pdf http://repository.unair.ac.id/89467/2/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Daftar%20isi.pdf http://repository.unair.ac.id/89467/3/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Daftar%20pustaka.pdf http://repository.unair.ac.id/89467/4/KKC%20KK%20KH%20246%20-%2019%20Ais%20e.pdf http://repository.unair.ac.id/89467/ http://lib.unair.ac.id |
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id-langga.894672019-10-19T07:09:16Z http://repository.unair.ac.id/89467/ EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL NIDIA KUSUMAWATI AISYAH, 061311133207 Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology This research aims was to observe liver histopathological features of mice toward the effect of Moringa oleifera leaves extract to reduce the damage of paracetamol administration. This research used 30 male mice aged 2-3 months with an average body weight of 20-30 grams and using completely randomized design (CRD) method with 5 repetitions for each groups. The negative control group was given 0.5% CMC Na and distilled water, the positive control was given 0.5% CMC Na and paracetamol, while treatments group one, two, and three were given Moringa leaf extract at a dose of 200 mg / kg, 400 mg / kg, 800 mg/kg respectively, then administered paracetamol. At the end of the research, mice are euthanized then liver collection was carried out. The liver collected was made into preparations using H.E staining to observe its histopathological features. According to the results of statistical analysis, there were significant differences (p <0.05) to the histopathological features of the liver in male mice induced by paracetamol between treatment groups. From the results obtained, it can be inferred that the right dose of Moringa oleifera leaves ethanol extract to reduce liver damage due to administration of paracetamol in male mice are 400 mg/ kgBW. 2019 Thesis NonPeerReviewed text id http://repository.unair.ac.id/89467/1/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Abstrak.pdf text id http://repository.unair.ac.id/89467/2/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Daftar%20isi.pdf text id http://repository.unair.ac.id/89467/3/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Daftar%20pustaka.pdf text id http://repository.unair.ac.id/89467/4/KKC%20KK%20KH%20246%20-%2019%20Ais%20e.pdf NIDIA KUSUMAWATI AISYAH, 061311133207 (2019) EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL. Skripsi thesis, UNIVERSITAS AIRLANGGA. http://lib.unair.ac.id |
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Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology |
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Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology NIDIA KUSUMAWATI AISYAH, 061311133207 EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL |
description |
This research aims was to observe liver histopathological features of mice
toward the effect of Moringa oleifera leaves extract to reduce the damage of
paracetamol administration. This research used 30 male mice aged 2-3 months
with an average body weight of 20-30 grams and using completely randomized
design (CRD) method with 5 repetitions for each groups. The negative control
group was given 0.5% CMC Na and distilled water, the positive control was
given 0.5% CMC Na and paracetamol, while treatments group one, two, and
three were given Moringa leaf extract at a dose of 200 mg / kg, 400 mg / kg, 800
mg/kg respectively, then administered paracetamol. At the end of the research,
mice are euthanized then liver collection was carried out. The liver collected was
made into preparations using H.E staining to observe its histopathological
features. According to the results of statistical analysis, there were significant
differences (p <0.05) to the histopathological features of the liver in male mice
induced by paracetamol between treatment groups. From the results obtained, it
can be inferred that the right dose of Moringa oleifera leaves ethanol extract to
reduce liver damage due to administration of paracetamol in male mice are 400
mg/ kgBW. |
format |
Theses and Dissertations NonPeerReviewed |
author |
NIDIA KUSUMAWATI AISYAH, 061311133207 |
author_facet |
NIDIA KUSUMAWATI AISYAH, 061311133207 |
author_sort |
NIDIA KUSUMAWATI AISYAH, 061311133207 |
title |
EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL |
title_short |
EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL |
title_full |
EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL |
title_fullStr |
EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL |
title_full_unstemmed |
EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL |
title_sort |
efek pemberian ekstrak ethanol daun kelor (moringa oleifera) terhadap gambaran histopatologi hepar mencit jantan yang diinduksi parasetamol |
publishDate |
2019 |
url |
http://repository.unair.ac.id/89467/1/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Abstrak.pdf http://repository.unair.ac.id/89467/2/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Daftar%20isi.pdf http://repository.unair.ac.id/89467/3/KKC%20KK%20KH%20246%20-%2019%20Ais%20e-Daftar%20pustaka.pdf http://repository.unair.ac.id/89467/4/KKC%20KK%20KH%20246%20-%2019%20Ais%20e.pdf http://repository.unair.ac.id/89467/ http://lib.unair.ac.id |
_version_ |
1681152675220029440 |