Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm
A new isoprenylated 4-phenylcoumarin derivative, mesucalophylloidin (1) along with three known compounds, mammea A/BA cyclo F (2), calolongic acid (3) and isocalolongic acid (4) were isolated from the stem bark of Mesua calophylloides (Ridl.) Kosterm. Structures of all the compounds were elucidated...
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Main Authors: | , , , |
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Format: | Article PeerReviewed |
Language: | English English English English |
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Taylor & Francis Online
2018
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Online Access: | http://repository.unair.ac.id/90963/1/C.04.%20Abstract.pdf http://repository.unair.ac.id/90963/2/C.04.%20Fulltext%20%28Karya%20Ilmiah%29.pdf http://repository.unair.ac.id/90963/3/C04_Validasi_Mesucalophylloidin%2C%20a%20new%20isoprenylated.pdf http://repository.unair.ac.id/90963/4/C04_Similarity.pdf http://repository.unair.ac.id/90963/ https://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1378215 https://doi.org/10.1080/14786419.2017.1378215 |
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Institution: | Universitas Airlangga |
Language: | English English English English |
Summary: | A new isoprenylated 4-phenylcoumarin derivative, mesucalophylloidin (1) along with three known compounds, mammea A/BA cyclo F (2), calolongic acid (3) and isocalolongic acid (4) were isolated from the stem bark of Mesua calophylloides (Ridl.) Kosterm. Structures of all the compounds were elucidated using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1–4 were evaluated for their cytotoxicity against P-388 cells, showing that compound 1 gave moderate activity with IC 50 6.26 μg/mL. |
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