Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm

A new isoprenylated 4-phenylcoumarin derivative, mesucalophylloidin (1) along with three known compounds, mammea A/BA cyclo F (2), calolongic acid (3) and isocalolongic acid (4) were isolated from the stem bark of Mesua calophylloides (Ridl.) Kosterm. Structures of all the compounds were elucidated...

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Main Authors: Mulyadi Tanjung, Fida Rachmadiarti, Ratih Dewi Saputri, Tjitjik Srie Tjahjandarie
Format: Article PeerReviewed
Language:English
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Published: Taylor & Francis Online 2018
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Online Access:http://repository.unair.ac.id/90963/1/C.04.%20Abstract.pdf
http://repository.unair.ac.id/90963/2/C.04.%20Fulltext%20%28Karya%20Ilmiah%29.pdf
http://repository.unair.ac.id/90963/3/C04_Validasi_Mesucalophylloidin%2C%20a%20new%20isoprenylated.pdf
http://repository.unair.ac.id/90963/4/C04_Similarity.pdf
http://repository.unair.ac.id/90963/
https://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1378215
https://doi.org/10.1080/14786419.2017.1378215
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spelling id-langga.909632020-03-13T02:35:44Z http://repository.unair.ac.id/90963/ Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm Mulyadi Tanjung Fida Rachmadiarti Ratih Dewi Saputri Tjitjik Srie Tjahjandarie Q Science (General) QD Chemistry A new isoprenylated 4-phenylcoumarin derivative, mesucalophylloidin (1) along with three known compounds, mammea A/BA cyclo F (2), calolongic acid (3) and isocalolongic acid (4) were isolated from the stem bark of Mesua calophylloides (Ridl.) Kosterm. Structures of all the compounds were elucidated using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1–4 were evaluated for their cytotoxicity against P-388 cells, showing that compound 1 gave moderate activity with IC 50 6.26 μg/mL. Taylor & Francis Online 2018 Article PeerReviewed image en http://repository.unair.ac.id/90963/1/C.04.%20Abstract.pdf text en http://repository.unair.ac.id/90963/2/C.04.%20Fulltext%20%28Karya%20Ilmiah%29.pdf text en http://repository.unair.ac.id/90963/3/C04_Validasi_Mesucalophylloidin%2C%20a%20new%20isoprenylated.pdf text en http://repository.unair.ac.id/90963/4/C04_Similarity.pdf Mulyadi Tanjung and Fida Rachmadiarti and Ratih Dewi Saputri and Tjitjik Srie Tjahjandarie (2018) Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm. Natural Product Research, 32 (9). pp. 1062-1067. ISSN 1478-6419 https://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1378215 https://doi.org/10.1080/14786419.2017.1378215
institution Universitas Airlangga
building Universitas Airlangga Library
country Indonesia
collection UNAIR Repository
language English
English
English
English
topic Q Science (General)
QD Chemistry
spellingShingle Q Science (General)
QD Chemistry
Mulyadi Tanjung
Fida Rachmadiarti
Ratih Dewi Saputri
Tjitjik Srie Tjahjandarie
Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm
description A new isoprenylated 4-phenylcoumarin derivative, mesucalophylloidin (1) along with three known compounds, mammea A/BA cyclo F (2), calolongic acid (3) and isocalolongic acid (4) were isolated from the stem bark of Mesua calophylloides (Ridl.) Kosterm. Structures of all the compounds were elucidated using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1–4 were evaluated for their cytotoxicity against P-388 cells, showing that compound 1 gave moderate activity with IC 50 6.26 μg/mL.
format Article
PeerReviewed
author Mulyadi Tanjung
Fida Rachmadiarti
Ratih Dewi Saputri
Tjitjik Srie Tjahjandarie
author_facet Mulyadi Tanjung
Fida Rachmadiarti
Ratih Dewi Saputri
Tjitjik Srie Tjahjandarie
author_sort Mulyadi Tanjung
title Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm
title_short Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm
title_full Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm
title_fullStr Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm
title_full_unstemmed Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm
title_sort mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from mesua calophylloides (ridl.) kosterm
publisher Taylor & Francis Online
publishDate 2018
url http://repository.unair.ac.id/90963/1/C.04.%20Abstract.pdf
http://repository.unair.ac.id/90963/2/C.04.%20Fulltext%20%28Karya%20Ilmiah%29.pdf
http://repository.unair.ac.id/90963/3/C04_Validasi_Mesucalophylloidin%2C%20a%20new%20isoprenylated.pdf
http://repository.unair.ac.id/90963/4/C04_Similarity.pdf
http://repository.unair.ac.id/90963/
https://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1378215
https://doi.org/10.1080/14786419.2017.1378215
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