HIPONATREMIA SEBAGAI FAKTOR PROGNOSIS KEMATIAN PASIEN MENINGOENSEFALITIS
Hyponatremia is the most common complication of intracranial lesions. Approximately 60.5% hyponatremia occurs in intracranial infection. The mortality rate of patients with severe degree of hyponatremia around 50% and 40% in moderate degree. The study of hyponatremia as a prognostic factor of mortal...
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Main Authors: | , |
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Format: | Theses and Dissertations NonPeerReviewed |
Published: |
[Yogyakarta] : Universitas Gadjah Mada
2012
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Subjects: | |
Online Access: | https://repository.ugm.ac.id/101115/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=57515 |
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Institution: | Universitas Gadjah Mada |
Summary: | Hyponatremia is the most common complication of intracranial lesions.
Approximately 60.5% hyponatremia occurs in intracranial infection. The
mortality rate of patients with severe degree of hyponatremia around 50% and
40% in moderate degree. The study of hyponatremia as a prognostic factor of
mortality in adult patients with meningoencephalitis in Indonesia has not been
done. The objective of this research is to assess hyponatremia as a prognostic
factor of mortality in patients with meningoencephalitis.
This research used a retrospective cohort study. Data were collected from
medical records of patients hospitalized in the department of Neurology at Dr.
Sardjito hospital, Yogyakarta. Meningoencephalitis diagnosed by ICD X code
G.03 dan G.04. Subjects were divided into 2 groups: 51.3% subjects in the
hyponatremia group and 48.7% subjects in the normonatremia as control.
Hypothesis testing using Chi-Square test for univariate analysis and multivariate
analysis using logistic regression.
Number of subjects included were 189 subjects, consisted of 55.6% males
and 44.4% women. The number of patients with hyponatremia group are 51.3%
and from the control group are 48.7%. Total patients with severe hyponatremia
was 5.3%, moderate hyponatremia was 20.6% and mild hyponatremia was 25.4%.
Form of univariate analysis hyponatremia had a significant prognostic risk of
mortality 2.76 times compared with control (95% CI |
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