( STUDI SALEP EKSTRAK DAUN BINAHONG Anredera cordifolia) FRAKSI ETANOL TERHADAP KESEMBUHAN LUKA IRIS SECARA FISIK PADA KULIT ANJING (Canis familiaris)

• Main Authors: , MUHAMMAD CHANDRA IMARULLAH, , drh. Slamet Raharjo, M.P.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2013
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/121140/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=61197
• Institution: Universitas Gadjah Mada

Dog was one of pet animals potentially get injuries. Binahong (Anredera cordifolia (Ten) Steenis) was one herb widely used as for curing wounds. The purpose of this research was to study the effect of the binahong leaf extract ointment ethanol fraction concentration of 5% and 10% toward wound healing in dogs skin physically. Four local female healthy dogs were used in this research. Dogs adapted for one week and given ivermectine as anthelmintic. Each dog treated with making of 6 cm long incision vertical direction by 3 incisions each dog. Three incisions were coded by A, B and C. The incision on group A as a control (not treated) had no medicinal treatment. The incision on group B were treated by giving ointment of binahong leaves extract ethanol fraction 5% and the incision on group on C were treated by giving ointment of binahong leaves extract ethanol fraction 10%. Observation of wound healing was done visually with parameters of wound swelling, redness of the wound, the wetness and the links between the two wound edges. The observations visually showed that there were little difference between group A (control), with group B (treated by giving ointment of binahong leaves extract ethanol fraction 5%) experienced a decrease swelling wound until day 3, while group C (treated by giving ointment of binahong leaves extract ethanol fraction 10%) decreased the intensity of swelling until day 2. The redness of the wound on A and B group did not show any longer on day 5 and on C group was not show anymore on day 4. Whereas the wetness and linked of two wound edges on A, B and C group were showing the same results achieved primary wound healing on day sixth. Based on the results and discussion, it could be concluded that the administration of binahong leaves extract ethanol fraction 10% ointment giving a positive effect on the acceleration of wound healing. The 10% ointment giving effect wound healing better than the 5% concentration and control physically. It was advisable for using binahong leaves extract ethanol fraction 10% ointment for treating wound on animal.